Table 1.
Cell line | GO accession | GO term | Number of genes | Adjusted p-value |
---|---|---|---|---|
MDA-MB-231 | GO:0030334 | regulation of cell migration | 5 | 2.0 × 10−2 |
GO:0030335 | positive regulation of cell migration | 4 | 2.3 × 10−2 | |
GO:2000145 | regulation of cell motility | 5 | 2.4 × 10−2 | |
GO:2000147 | positive regulation of cell motility | 4 | 2.5 × 10−2 | |
GO:0051272 | positive regulation of cellular component movement | 4 | 2.7 × 10−2 | |
T-47D | GO:0048513 | animal organ development | 45 | 2.6 × 10−8 |
GO:0035556 | intracellular signal transduction | 41 | 4.5 × 10−8 | |
GO:0009887 | organ morphogenesis | 22 | 4.0 × 10−7 | |
GO:0009966 | regulation of signal transduction | 36 | 4.5 × 10−6 | |
GO:0007166 | cell surface receptor signaling pathway | 34 | 9.5 × 10−5 |
The DAVID Functional Annotation Tools was used to reveal significantly enriched GO categories among the differentially expressed protein-coding genes. The analysis was done independently for each cell line and shared differentially expressed genes were omitted. The top five biological function GO terms are shown