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. 2017 Jan 11;17:46. doi: 10.1186/s12885-016-2988-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — MALAT1 silencing induced apoptosis and cell cycle arrest. AGS and MKN74 cells were transfected with siMALAT1 or siCT, and apoptosis was detected by PI/Annexin V staining (a). Cell cycle arrest was analyzed by PI staining (b). The increased expression of RASSF6 by qRT-PCR and western blot (c). The decreased colony forming rate by siMALAT1_2 compared to siCT (d). The data shown in the panels are representative of three independent experiments. Data shown represent the mean ± s.e.m. Asterisks represent a statistically significant difference from the scrambled control (*P ≤ 0.05)