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. 2017 Jan 11;5:5. doi: 10.1186/s40478-016-0407-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — PCBP1 mRNA targets have larger UTRs and share a common recognition sequence. a The average length of the 5′UTRs present in the top 50 high and low enriched genes was compared to the average length of the mouse 5′UTRome. Wilcoxon rank sum test, p ≤ 0,001. The same analysis was performed in (b) with the 3′UTR present in the top 50 genes of high and low enriched genes. Wilcoxon rank sum test; p ≤ 0,001. c PCBP1 mRNA targets share a common recognition sequence that is rich in poly(C) repeat stretches. This RNA motif was identified by subjecting the most stringent set of PCBP1 targets, above ≥ 2-fold, to MEME analysis. d Table with statistics showing the enrichment of the RNA motif in values