Table 2.

Clinically relevant variants detected by PHIAL

		Coverage		Allelic fraction
Gene	Variant	Primary	Relapse	Primary	Relapse
TP53	Missense_Mutation	35	37	0.66	0.62
NOTCH2	Nonsense_Mutation	24	26	0.58	0.27
EP300	Missense_Mutation	55	63	0.31	0.33
DNMT3A	Splice_Site	52	NA	0.08	NA
EZH2	Missense_Mutation	37	NA	0.3	NA
FBWX7	Missense_Mutation	NA	64	NA	0.38
FIP1L1	Splice_Site	NA	59	NA	0.37