Table 3.
Predicted classification | Primary tumor (H302) | Relapse tumor (H385) |
---|---|---|
Probability of BAGS | 0.595 | 0.363 |
BAGS class | Centrocyte | Memory |
Probability of ABC | 1.19E + 09 | 1.09E − 01 |
ABC-GCB-NC class | GCB | NC |
Probability of R | 0.034 | 0.049 |
R class | Sensitive | Sensitive |
Probability of C | 0.662 | 0.225 |
C class | Resistant | Sensitive |
Probability of H | 0.963 | 0.041 |
H class | Resistant | Sensitive |
Probability of O | 0.750 | 0.639 |
O class | Resistant | Resistant |
Probability of Dex | 0.023 | 0.037 |
Dex class | Resistant | Resistant |
Probability combined | 0.993 | 0.022 |
Combined class | Resistant | Sensitive |
The probability of resistance towards cyclophosphamide (C), doxorubicin, (H), vincristine (O), and rituximab (R) determined by applying the REGS classification (Dybkaer et al. [18] and Laursen et al. [19] in preparation) onto .CEL files from Affymetrix U133plus2.0 arrays of the indicated samples through http://www.hemaclass.org. A probability close to 1 predicts resistance, whereas a value close to 0, predicts sensitivity to the indicated drug
NC not classified