Table 4. Differentially regulated functional gene sets identified with the Global Test.

Term ID	Description	P-value	Count
Molecular Function
GO:0004602	Glutathione peroxidase activity	0.0013	11
GO:0015278	Calcium-release channel activity	0.0083	11
GO:0043560	Insulin receptor substrate binding	0.0085	11
GO:0031490	Chromatin DNA binding	0.0100	49
Biological process
GO:0009235	Cobalamin metabolic process	0.0014	13
GO:0001573	Ganglioside metabolic process	0.0025	16
GO:0045682	Regulation of epidermis development	0.0026	30
GO:0046033	AMP metabolic process	0.0037	13
GO:0019082	Viral protein processing	0.0044	10
GO:1901068	Guanosine-containing compound metabolic process	0.0047	24
GO:0033194	Response to hydroperoxide	0.0060	14
GO:0007220	Notch receptor processing	0.0061	18
GO:0035357	Peroxisome proliferator activated receptor signaling pathway	0.0066	12
GO:0008206	Bile acid metabolic process	0.0077	20
GO:0032515	Negative regulation of phosphoprotein phosphatase activity	0.0083	13
GO:0070987	Error-free translesion synthesis	0.0091	14
GO:0045123	Cellular extravasation	0.0097	29
Reactome
R-HSA-1660661	Sphingolipid de novo biosynthesis	0.0022	24
R-HSA-428157	Sphingolipid metabolism	0.0043	48
R-HSA-977444	GABA B receptor activation	0.0064	18
R-HSA-977443	GABA receptor activation	0.0066	19
R-HSA-997272	Inhibition of voltage gated Ca2+channels via Gbeta/gamma subunits	0.0074	11
R-HSA-400042	Inhibition of insulin secretion by adrenaline noradrenaline	0.0075	16
R-HSA-1296065	Inwardly rectifying K channels	0.0089	12