TABLE 2. Main nodes affected in esophageal carcinoma.

	Esophageal topography and histology
Lymph-nodal metastasis	Cervical SCC	Middle SCC	Distal SCC	EA	Total	p
	(n=50)	(n=224)	(n=102)	(n=91)	(n=467)
Pre vascular	5 (10,0)	14 (6,3)	5 (4,9)	0 (0,0)	24 (5,1)	0,007#
Retrocrural space	1 (2,0)	6 (2,7)	5 (4,9)	0 (0,0)	12 (2,6)	0,087#
Hepatogastric ligament	3 (6,0)	37 (16,5)	23 (22,5)	28 (30,8)	91 (19,5)	0,002
Peripancreatic	1 (2,0)	4 (1,8)	8 (7,8)	7 (7,7)	20 (4,3)	0,021#
Hepatic hilum	2 (4,0)	3 (1,3)	4 (3,9)	9 (9,9)	18 (3,9)	0,010#
Perigastric	1 (2,0)	15 (6,7)	19 (18,6)	18 (19,8)	53 (11,3)	<0,001
Perispleic	0 (0,0)	3 (1,3)	0 (0,0)	1 (1,1)	4 (0,9)	0,362#
Perigastroesophageal junction	0 (0,0)	2 (0,9)	3 (2,9)	1 (1,1)	6 (1,3)	0,356#
Celiac trunk	3 (6,0)	16 (7,1)	12 (11,8)	11 (12,1)	42 (9,0)	0,325#
Paratracheal	19 (38,0)	95 (42,4)	26 (25,5)	14 (15,4)	154 (33,0)	<0,001
Subcarinal	13 (26,0)	74 (33,0)	16 (15,7)	13 (14,3)	116 (24,8)	<0,001
Pulmonary hilum	4 (8,0)	37 (16,5)	13 (12,7)	13 (14,3)	67 (14,3)	0,438
Subaortic	2 (4,0)	24 (10,7)	5 (4,9)	3 (3,3)	34 (7,3)	0,046#
Periesophagic	22 (44,0)	90 (40,2)	33 (32,4)	36 (39,6)	181 (38,8)	0,465
Cardiophrenic	0 (0,0)	3 (1,3)	1 (1,0)	3 (3,3)	7 (1,5)	0,355#
Supraclavicular	4 (8,0)	18 (8,0)	3 (2,9)	6 (6,6)	31 (6,6)	0,307#
Cervical	13 (26,0)	25 (11,2)	3 (2,9)	6 (6,6)	47 (10,1)	<0,001
Portocava space	0 (0,0)	3 (1,3)	5 (4,9)	0 (0,0)	8 (1,7)	0,027#
Periaortic	3 (6,0)	24 (10,7)	13 (12,7)	0 (0,0)	40 (8,6)	<0,001#
Interaortocaval space	3 (6,0)	12 (5,4)	8 (7,8)	0 (0,0)	23 (4,9)	0,012#
Axillary node/Retropectoral	0 (0,0)	5 (2,2)	0 (0,0)	0 (0,0)	5 (1,1)	0,060#
Aortopulmonary window	1 (2,0)	5 (2,2)	0 (0,0)	0 (0,0)	6 (1,3)	0,091#

Chi-Square test; #=likelihood ratio test; SCC=squamous carcinoma; EA=esophageal adenocarcinoma. The numbers in brackets refer to the percentage.