Figure 1.

Anatomical location of fibre bundle regions of interest used for statistical comparison. The inset for each fibre bundle illustrates representative tracts reconstructed for a single subject, with the solid black line indicating the AFQ-identified tract core used for calculation of the tract profiles. Tract cores for each subject are mapped to a template image and averaged to indicate the group-wise representation of each fibre bundle. For statistical comparison, each fibre bundle is divided into five regions of interest by averaging every 20 consecutive tract sections. Region of interest numbers correspond to the regions of interest used in Fig. 2 and Supplementary Table 1. FF = fimbria-fornix; PWMB = parahippocampal white matter bundle; UF = uncinate fasciculus.