. Author manuscript; available in PMC: 2017 Jan 11.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2016 Sep 3;96(5):1054–1059. doi: 10.1016/j.ijrobp.2016.08.042

Table 4.

Comparison of Standardized Grade 3 Toxicities Among Prospective APBI Trials

Trial	APBI Technique	n	Follow-up	Incidence G3
RAPID¹⁴ NSABP B-	3D-CRT	1070	3 yrs	1.4%
39/RTOG 0413¹⁵	3D-CRT	1524	5.9 yrs	0 – 3%
RTOG 9517¹⁶	Multi-Catheter	100	7.6 yrs	21% - LDR 8% - HDR
RTOG 0319	3D-CRT	54	8 yrs	7.7%

APBI–Accelerated Partial Breast Irradiation; G–Grade; 3D-CRT–3 Dimensional Conformal Radiation Therapy; LDR–Low Dose-Rate; HDR–High Dose-Rate