Table 2.

White blood cell and platelet values in the dogs at predose and at 5, 40, and 120 min and 24 h postinjection

Group	Dose (ml/kg)	US activation	WBC (109/L)					Platelets (109/L)
			Predose	5 min	40 min	120 min	24 h	Predose	5 min	40 min	2 h	24 h
1	0	No	10.25 ± 1.04	9.40 ± 1.35	10.40 ± 0.48	9.20 ± 0.77	10.58 ± 0.99	389 ± 81	342 ± 58	330 ± 48	365 ± 82	350 ± 78
2	0.1	No	11.95 ± 1.99	10.25 ± 1.11	9.93 ± 0.91	10.05 ± 1.09	11.63 ± 2.50	338 ± 116	266 ± 70	322 ± 112	318 ± 93	316 ± 101
3	0.3	No	11.03 ± 1.41	4.83 ± 0.62b	7.30 ± 0.71b	9.43 ± 0.91	10.53 ± 2.57	344 ± 109	169 ± 80b	284 ± 74	311 ± 81	295 ± 88
4	1.0	No	12.00 ± 2.02	3.05 ± 1.96b	8.83 ± 0.43a	10.13 ± 0.81	10.18 ± 1.18	249 ± 72	53 ± 21b	191 ± 57	213 ± 57	207 ± 58
5	0	Yes	12.55 ± 0.93	12.05 ± 1.98	12.50 ± 2.32	12.03 ± 2.08	11.53 ± 2.49	343 ± 45	355 ± 42	349 ± 43	341 ± 55	355 ± 54
6	0.1	Yes	11.38 ± 1.52	8.95 ± 0.86a	6.98 ± 1.35a	9.83 ± 2.10	11.03 ± 0.35	362 ± 90	342 ± 112	340 ± 84	344 ± 97	344 ± 88
7	0.3	Yes	11.35 ± 1.47	5.65 ± 2.19b	8.70 ± 1.22a	9.28 ± 1.78	11.35 ± 0.65	282 ± 51	174 ± 69b	262 ± 48	242 ± 90	287 ± 63
8	1.0	Yes	10.95 ± 2.85	2.25 ± 0.79b	8.90 ± 1.84a	9.78 ± 1.60	9.55 ± 1.91	295 ± 46	94 ± 29b	242 ± 38a	270 ± 44	267 ± 42

^a P < 0.05: Group 2, 3, and 4 versus group 1 or group 6, 7, and 8 versus group 5.

^b P < 0.01: Group 2, 3, and 4 versus group 1 or group 6, 7, and 8 versus group 5.