Figure 3. Systematic administration of CX546 relieves depression-like behaviors in paw incision (PI)-treated rats.
A. Intraperitoneal administration of CX546 (10mg/kg) relieved depression-like behaviors in PI-treated rats, as shown by a decrease of immobility during the FST, compared with control group. Unpaired two-tailed Student's t-test, Dimethyl sulfoxide (DMSO) group n=3; CX546 group n=3, *p=0.0486. B. Systemic administration of CX546 (10mg/kg) did not change locomotion in PI-treated rats, compared with DMSO injection. Two-way ANOVA with repeated measures, DMSO group n=7; CX546 group n=7, p=0.8364.
