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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Anesthesiology. 2016 Nov;125(5):1030–1043. doi: 10.1097/ALN.0000000000001336

Figure 7. Local infusion of CX546 into the nucleus accumbens (NAc) relieves depression-like behaviors in spared nerve injury (SNI)-treated rats.

Figure 7

A. Intra-NAc infusion of CX546 (800uM/ul) diminished depression-like behaviors in SNI-treated rats, as shown by a decrease of immobility during the force swim test (FST). Unpaired two-tailed Student's t-test, Saline group n=8; CX546 group n=7, *p=0.0199. B. Intra-NAc infusion of CX546 (800uM/ul) did not change the locomotion of SNI rats, compared with saline infusion. Two-way ANOVA with repeated measures and Bonferroni post-test, Saline group n=4; CX546 group n=7, p=0.9782.