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. Author manuscript; available in PMC: 2017 Jan 11.
Published in final edited form as: Behav Brain Res. 2015 Jun 16;292:83–94. doi: 10.1016/j.bbr.2015.06.023

Figure 2. Correlation between water-maze performance and body weight gain in BXD RI strains after 4-month HFD treatment.

Figure 2

(A) Comparison of the body weight of high fat diet induced-obesity mice after 4 months of consumption. Data are represented as mean ± SEM from each time-point (i.e. 0, 3 or 4 months of diets). Strains are arranged from smallest to largest body weight gain (left to right). (B) The average escape latency (error bar represents SEM, n=8–18/group) is shown for each BXD RI strain and the parent C57BL/6 strain. (C) A strong correlation exists between the percentage of body weight gain and the average escape latency in B BXD strains after 4 months of HFD consumption. The number next to each data point refers to the BXD strain number (P<0.05, r=0.81).