Table 1. Metformin stimulates glucose uptake in H295R.

Metformin (mM)	Glucose uptake (% increase)	SE	P value
0	100.0	5.98	-
10	165.6	6.38	0.000
20	161.8	5.21	0.000
50	126.1	3.19	0.002

The 2-deoxy-[³H] D-glucose uptake was measured in H295R cells treated for 24 hours with metformin and detected as radioactive counts per minute (CPM) on a scintillation beta counter. Data are expressed as mean ± SE of percentage increase of glucose uptake vs. control without metformin (0 mM). P values obtained by statistical analysis performed with ANOVA followed by Dunnett's post hoc test vs. control are indicated.