Table 1. Characteristics of patients with hepatocellular carcinoma (n = 69).
Variable | Total (n = 69) | Recurrence (n = 32) | Non-recurrence (n = 37) | P-value |
---|---|---|---|---|
Sex (M:F) | 51:18 | 24:8 | 27:10 | 1.000 |
Age (years) | 60.2 ± 10.9 | 60.3 ± 8.5 | 60.2 ± 12.7 | 0.971 |
Body mass index | 24.6 ± 3.4 | 24.5 ± 4.1 | 24.7 ± 2.8 | 0.785 |
Alcohol | 18.8% (13/69) | 15.6% (5/32) | 21.6% (8/37) | 0.556 |
Smoking | 21.7% (15/69) | 15.6% (5/32) | 27.0% (10/37) | 0.381 |
Fatty liver | 30.4% (21/69) | 18.8% (6/32) | 40.5% (15/37) | 0.068 |
HBsAg (+) | 55.1% (38/69) | 59.4% (19/32) | 51.4% (19/37) | 0.628 |
HCV RNA (+) | 27.5% (19/69) | 37.5% (12/32) | 24.3% (9/37) | 0.298 |
HBsAg (+) and HCV RNA (+) | 2.9% (2/69) | 3.1% (1/32) | 2.7% (1/37) | 1.000 |
Knodell inflammation score | 3.7 ± 2.0 | 4.1 ± 1.7 | 3.4 ± 2.2 | 0.131 |
Ishak fibrosis score | 4.0 ± 1.7 | 4.4 ± 1.7 | 3.6 ± 1.6 | 0.056 |
Liver cirrhosis | 37.7% (26/69) | 50% (16/32) | 27.0% (10/37) | 0.080 |
ALT (U/L) | 53.2 ± 38.5 | 62.3 ± 42.6 | 45.3 ± 33.2 | 0.067 |
AST (U/L) | 53.4 ± 31.9 | 60.1 ± 33.8 | 47.6 ± 29.4 | 0.104 |
Albumin (g/dL) | 4.4 ± 0.3 | 4.3 ± 0.3 | 4.6 ± 0.3 | 0.002 |
Total bilirubin (mg/dL) | 0.7 ± 0.4 | 0.7 ± 0.2 | 0.8 ± 0.4 | 0.143 |
Prolongation of prothrombin time (sec) | 0.6 ± 0.7 | 0.7 ± 0.7 | 0.6 ± 0.7 | 0.436 |
Creatinine (mg/dL) | 1.2 ± 1.2 | 1.5 ± 1.7 | 0.9 ± 0.4 | 0.086 |
α-fetoprotein (ng/mL) | 425.9 ± 1219.4 | 589.6 ± 1469.6 | 284.2 ± 950.9 | 0.303 |
TNM stage (1:2:3) | 22:36:11 | 7:14:11 | 15:22:0 | < 0.001a |
Follow up time (days) | 928 ± 347 | 877.7 ± 373.7 | 970.8 ± 320.7 | 0.269 |
Mortality | 10.1% (7/69) | 18.8% (6/32) | 2.7% (1/37) | 0.044 |
Data are percentage or mean (standard deviation). Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; HBsAg, hepatitis B virus surface antigen; HCV, hepatitis C virus. A 2-tailed independent t test was used for continuous variables between recurrence and non-recurrence groups. Comparisons of nominal values were by Fisher's exact test except TNM stage.
By a Pearson Chi square test.