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. 2016 Jun 20;7(31):49765–49776. doi: 10.18632/oncotarget.10176

Table 1. Characteristics of patients with hepatocellular carcinoma (n = 69).

Variable Total (n = 69) Recurrence (n = 32) Non-recurrence (n = 37) P-value
Sex (M:F) 51:18 24:8 27:10 1.000
Age (years) 60.2 ± 10.9 60.3 ± 8.5 60.2 ± 12.7 0.971
Body mass index 24.6 ± 3.4 24.5 ± 4.1 24.7 ± 2.8 0.785
Alcohol 18.8% (13/69) 15.6% (5/32) 21.6% (8/37) 0.556
Smoking 21.7% (15/69) 15.6% (5/32) 27.0% (10/37) 0.381
Fatty liver 30.4% (21/69) 18.8% (6/32) 40.5% (15/37) 0.068
HBsAg (+) 55.1% (38/69) 59.4% (19/32) 51.4% (19/37) 0.628
HCV RNA (+) 27.5% (19/69) 37.5% (12/32) 24.3% (9/37) 0.298
HBsAg (+) and HCV RNA (+) 2.9% (2/69) 3.1% (1/32) 2.7% (1/37) 1.000
Knodell inflammation score 3.7 ± 2.0 4.1 ± 1.7 3.4 ± 2.2 0.131
Ishak fibrosis score 4.0 ± 1.7 4.4 ± 1.7 3.6 ± 1.6 0.056
Liver cirrhosis 37.7% (26/69) 50% (16/32) 27.0% (10/37) 0.080
ALT (U/L) 53.2 ± 38.5 62.3 ± 42.6 45.3 ± 33.2 0.067
AST (U/L) 53.4 ± 31.9 60.1 ± 33.8 47.6 ± 29.4 0.104
Albumin (g/dL) 4.4 ± 0.3 4.3 ± 0.3 4.6 ± 0.3 0.002
Total bilirubin (mg/dL) 0.7 ± 0.4 0.7 ± 0.2 0.8 ± 0.4 0.143
Prolongation of prothrombin time (sec) 0.6 ± 0.7 0.7 ± 0.7 0.6 ± 0.7 0.436
Creatinine (mg/dL) 1.2 ± 1.2 1.5 ± 1.7 0.9 ± 0.4 0.086
α-fetoprotein (ng/mL) 425.9 ± 1219.4 589.6 ± 1469.6 284.2 ± 950.9 0.303
TNM stage (1:2:3) 22:36:11 7:14:11 15:22:0 < 0.001a
Follow up time (days) 928 ± 347 877.7 ± 373.7 970.8 ± 320.7 0.269
Mortality 10.1% (7/69) 18.8% (6/32) 2.7% (1/37) 0.044

Data are percentage or mean (standard deviation). Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; HBsAg, hepatitis B virus surface antigen; HCV, hepatitis C virus. A 2-tailed independent t test was used for continuous variables between recurrence and non-recurrence groups. Comparisons of nominal values were by Fisher's exact test except TNM stage.

a

By a Pearson Chi square test.