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. 2016 Jun 27;7(31):49998–50016. doi: 10.18632/oncotarget.10307

Figure 1. Mammary carcinoma cells exchange vesicles with nontransformed mammary fibroblasts.

Figure 1

Panels a. and b. present confocal images showing exchange of vesicular structures between fibroblasts (green) and tumor cells (red, arrows in panels a and b). Orthogonal projections verify the presence of tumor vesicles inside fibroblasts (arrowheads in panels a and b). Panel c. presents quantitation of vesicle transfer as numbers of vesicles transferred in a field containing 20 cells (mean+SEM, n≥5). Single, double, and triple asterisks indicate statistically significant differences of p<0.05, p<0.01 and p<0.001, respectively. Scale bars = 20 μm.