Table 3. Comparison of the predictive accuracy of the prognostic models.

Prognostic model	Overall survival		Recurrence-free survival
	C-index	P	C-index	P
MUC3A signature	0.679		0.679
UISS	0.723		0.724
UISS + MUC3A signature	0.781	< 0.001	0.779	< 0.001
SSIGN	0.768		0.756
SSIGN + MUC3A signature	0.830	0.002	0.812	0.004
Leibovich	0.820		0.815
Leibovich +MUC3A signature	0.859	0.003	0.847	0.011

C-index Harrell's concordance index, UISS University of California Los Angeles Integrated Staging System, SSIGN stage, size, grade, and necrosis