Table 1. Characteristics of PDX tumors and their corresponding CRC patients.
| PDX histology | Pathology | Preoperative chemotherapy | TNMa | Mouse strain | Days for growthb | |
|---|---|---|---|---|---|---|
| KUC1 | CRCc | mod.c | None | pT3 pN1 cM1 | NOD/SCID | 75 |
| KUC2 | CRC | mod. | None | pT4a pN0 cM1 | NOD/SCID | 30 |
| KUC3 | No tumor | mod. | None | pT4a pN2 cM0 | NOD/SCID | - |
| KUC4 | DLBCLc | mod. | Noned | pT2 pN0 cM0 | NOD/SCID | 28 |
| KUC5 | CRC | mod. | None | pT3 pN0 cM1 | NOD/SCID | 176 |
| KUC6 | CRC | mod. | None | pT3 pN1 cM0 | NSG | 223 |
| KUC7 | CRC | mod. | None | pT2 pN0 cM0 | NSG | 35 |
| KUC8 | CRC | mod. | None | pT4a pN1 cM1 | NSG | 47 |
| KUC9 | CRC | mod. | None | pT4b pN0 cM0 | NSG | 19 |
| KUC10 | No tumor | mod. | None | pT3 pN0 cM0 | NSG | - |
| KUC11 | DLBCL | well.c | None | pT3 pN1 cM0 | NSG | 55 |
| KUC12 | No tumor | well. | None | pT3 pN1 cM1 | NSG | - |
| KUC13 | No tumor | mod. | Yes | pT3 pN2 cM1 | NSG | - |
a
TNM classification (7th edition) in clinical pathological reports.
b
Number of days when PDX tumor reached 0.5 cm3 after xenotransplantation of patient specimen.
c
Abbreviations: CRC, colorectal cancer; DLBCL, diffuse large B cell lymphoma; mod, moderately-differentiated adenocarcinoma; well, well-differentiated adenocarcinoma.
d
None, but under an immunosuppressive therapy after organ transplantation.