Table 4. Candidate lncRNAs and clinicopathological factors for predicting liver metastases in patients with stage I/II CRC.

Factors	Subset	Univariate		Multivariate
		P value	Relative risk	95% CI	P value
Age (year)	≤ 50 / > 50	0.0399	0.3	0.10 - 0.86	0.0257
Gender	Male / Female	0.3334	-	-	-
Organ	Colon / Rectum / C&R	0.1455	-	-	-
Deptha	T1 / T2 / T3 / T4	0.0137	2.2	1.16 - 4.29	0.0173
LVI	Positive / Negative	0.6198	-	-	-
Histologic grade	I / II / III	0.0317	2.6	0.95 - 7.24	0.0644
GAS5	High / Low	0.0206	3.3	0.77 - 14.55	0.1105
H19	High / Low	0.2474	-	-	-
MEG3	High / Low	0.2024	-	-	-
Yiya	High / Low	0.0005	10.7	3.40 - 33.52	0.0001

^aAccording to Tumor-Node-Metastasis (TNM) Classification of Colorectal Carcinoma

High, high expression level ≥ mean 2^ΔCq

Low, low expression level < mean 2^ΔCq

CRC, colorectal cancer

C, colon; R, rectum; LVI, lymphatic vessel invasion; CI, confidence interval