Table 2. Analysis of bivariate association of the relative mean expression of 15 investigated genes between NSCLC cases and non-cancer controls.

Gene	Total Sample		NSCLC Cases		Non-cancer Controls		p§
	Mean	SD	Mean	SD	Mean	SD
Significant Lower Mean Expression in NSCLC Cases
EIF2S3	3.56	0.53	3.46	0.65	3.61	0.43	0.0028***
EXT2	−0.71	0.65	−0.83	0.74	−0.63	0.58	0.0008***
RNF4	2.03	0.58	1.92	0.58	2.09	0.57	0.0017***
WEE1	−0.59	0.67	−0.86	0.71	−0.42	0.59	0.0000***
Significant Higher Mean Expression in NSCLC Cases
CPEB4	0.75	1.03	1.14	1.13	0.51	0.88	0.0000***
DUSP6	1.93	0.81	2.47	0.79	1.61	0.63	0.0000***
GRB2	2.16	0.79	2.44	0.84	1.99	0.71	0.0000***
MCM4	−1.84	0.68	−1.73	0.72	−1.90	0.65	0.0093***
MDM2	−0.76	0.64	−0.49	0.72	−0.92	0.52	0.0000***
MMD	1.61	1.06	1.79	1.22	1.50	0.93	0.0034***
STAT2	1.88	0.59	1.99	0.68	1.81	0.52	0.0008***
No Significant Difference of Mean Expression Between Two Groups
IRF4	0.23	0.69	0.23	0.72	0.23	0.67	0.9488
NF1	0.86	0.47	0.82	0.57	0.88	0.40	0.2078
POLDIP2	2.42	0.70	2.46	0.74	2.40	0.67	0.4122
ZNF264	−2.33	0.58	−2.29	0.62	−2.36	0.54	0.1998

^§The p value was obtained from the independent two-sample t-test.

^***:The gene expression level between NSCLC cases and non-cancer controls was significantly different (p < 0.05).