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. 2016 May 18;7(31):50612–50623. doi: 10.18632/oncotarget.9437

Table 1. The basic clinical characteristics in HCC patients (n=102) and control subjects (n=105).

Variables Control HCC P-value
Gender <0.01
 Male (n, %) 37 (35.2%) 86 (84.3%)
 Female (n, %) 68 (64.8%) 16 (15.7%)
Smoking <0.01
 Yes (n, %) 12 (11.9%) 45 (44.1%)
 No (n, %) 89 (88.1%) 57 (55.9%)
Drinking (n, %) <0.01
 Yes 12 (11.9%) 37 (36.3%)
 No 89 (88.1%) 65 (63.7%)
Age <0.05
Average ± S.D. (years) 48 ± 10 53 ± 11
 < 44 year (n, %) 35 (33.3%) 21 (20.6%)
 45-59 year (n, %) 56 (53.3%) 51 (50.0%)
 60-74 year (n, %) 13 (12.4%) 29 (28.4%)
 > 75 year (n, %)
1 (1.0%) 1 (1.0%)

HbsAg
anti-HCV
Pathologyclassification
Negative (n=105)
Negative (n=105)
Normal (n=105)
Positive (n=96)
Positive (n=6)
S1, S2, S3, S4.
Diagnosis liver hemangioma (n=84)
metastatic carcinoma (n=8)
cholelithiasis (n=9)
gallbladder cancer (n=4)
HCC (n=102)

S1: portal area fibrosis expand, and confined in the hepatic sinus and lobule (n=8); S2: fibrosis around portal area, fibrous septums form, lobule structure keep (n=19); S3: fibrous septums and lobule structure disorder, without cirrhosis (n=27); S4: early stage cirrhosis (n=48). HCC indicates hepatocellular carcinoma. n=number. P value for comparison between the controls and HCC sets.