Table 5.
Hormone | PFOS | PFOA | ||
---|---|---|---|---|
β (95% CI) | p-Value | β (95% CI) | p-Value | |
Cortisol | ||||
Crude | –0.774 (–1.19, –0.356) | < 0.001 | 0.231 (–0.083, 0.546) | 0.149 |
Adjusteda | –0.844 (–1.31, –0.378) | < 0.001 | 0.244 (–0.119, 0.607) | 0.186 |
Cortisone | ||||
Crude | –1.11 (–1.68, –0.555) | < 0.001 | 0.222 (–0.205, 0.650) | 0.306 |
Adjusteda | –1.15 (–1.79, –0.515) | < 0.001 | 0.390 (–0.108, 0.889) | 0.124 |
DHEA | ||||
Crude | 0.342 (0.120, 0.564) | 0.002 | –0.155 (–0.320, 0.009) | 0.064 |
Adjusteda | 0.365 (0.112, 0.618) | 0.004 | –0.250 (–0.442, –0.058) | 0.010 |
Androstenedione | ||||
Crude | –0.038 (–0.212, 0.134) | 0.657 | –0.099 (–0.225, 0.026) | 0.119 |
Adjusteda | –0.013 (–0.208, 0.181) | 0.893 | –0.105 (–0.251, 0.041) | 0.157 |
Cortisol/cortisone | ||||
Crude | 0.344 (0.086, 0.602) | 0.009 | 0.008 (–0.183, 0.200) | 0.928 |
Adjusteda | 0.312 (0.025, 0.599) | 0.032 | –0.146 (–0.364, 0.072) | 0.188 |
Cortisol/DHEA ratio | ||||
Crude | –1.11 (–1.71, –0.516) | < 0.001 | 0.386 (–0.064, 0.838) | 0.092 |
Adjusteda | –1.21 (–1.88, –0.531) | < 0.001 | 0.494 (–0.030, 1.02) | 0.064 |
Glucocorticoid/androgenic hormones ratio | ||||
Crude | –1.24 (–1.89, –0.608) | < 0.001 | 0.368 (–0.115, 0.852) | 0.134 |
Adjusteda | –1.33 (–2.05, –0.601) | < 0.001 | 0.551 (–0.013, 1.11) | 0.057 |
Both exposure and outcome measures were log10 transformed. aFully adjusted for gestational age, maternal age, parity, smoking and caffeine intake during pregnancy, maternal educational level, and blood sampling period. |