. 2016 May 24;125(1):111–118. doi: 10.1289/EHP142

Table 5.

Association of prenatal PFC levels with cord blood glucocorticoids and androgenic hormones (n = 185).

Hormone	PFOS		PFOA
Hormone	β (95% CI)	p-Value	β (95% CI)	p-Value
Cortisol
Crude	–0.774 (–1.19, –0.356)	< 0.001	0.231 (–0.083, 0.546)	0.149
Adjusted^a	–0.844 (–1.31, –0.378)	< 0.001	0.244 (–0.119, 0.607)	0.186
Cortisone
Crude	–1.11 (–1.68, –0.555)	< 0.001	0.222 (–0.205, 0.650)	0.306
Adjusted^a	–1.15 (–1.79, –0.515)	< 0.001	0.390 (–0.108, 0.889)	0.124
DHEA
Crude	0.342 (0.120, 0.564)	0.002	–0.155 (–0.320, 0.009)	0.064
Adjusted^a	0.365 (0.112, 0.618)	0.004	–0.250 (–0.442, –0.058)	0.010
Androstenedione
Crude	–0.038 (–0.212, 0.134)	0.657	–0.099 (–0.225, 0.026)	0.119
Adjusted^a	–0.013 (–0.208, 0.181)	0.893	–0.105 (–0.251, 0.041)	0.157
Cortisol/cortisone
Crude	0.344 (0.086, 0.602)	0.009	0.008 (–0.183, 0.200)	0.928
Adjusted^a	0.312 (0.025, 0.599)	0.032	–0.146 (–0.364, 0.072)	0.188
Cortisol/DHEA ratio
Crude	–1.11 (–1.71, –0.516)	< 0.001	0.386 (–0.064, 0.838)	0.092
Adjusted^a	–1.21 (–1.88, –0.531)	< 0.001	0.494 (–0.030, 1.02)	0.064
Glucocorticoid/androgenic hormones ratio
Crude	–1.24 (–1.89, –0.608)	< 0.001	0.368 (–0.115, 0.852)	0.134
Adjusted^a	–1.33 (–2.05, –0.601)	< 0.001	0.551 (–0.013, 1.11)	0.057
Both exposure and outcome measures were log₁₀ transformed. ^aFully adjusted for gestational age, maternal age, parity, smoking and caffeine intake during pregnancy, maternal educational level, and blood sampling period.