. 2016 Aug 5;125(1):8–14. doi: 10.1289/EHP171

Table 1.

Pregnancy characteristics and prevalence of critical and noncritical heart defects, 2–8 weeks postconception, Quebec, April through September, 1988–2012.

Characteristic	Total no. of infants	Critical defect		Noncritical defect
Characteristic	Total no. of infants	No. of infants with defects	Prevalence per 100,000 (95% confidence interval)	No. of infants with defects	Prevalence per 100,000 (95% confidence interval)
No. of days ≥ 30°C^a
0 days	218,337	172	78.8 (67.4, 91.5)	1,753	802.9 (765.9, 841.2)
1–2 days	182,430	141	77.3 (65.1, 91.1)	1,552	850.7 (809.1, 893.9)
3–9 days	262,300	187	71.3 (61.4, 82.3)	2,261	862.0 (827.0, 898.1)
≥ 10 days	41,142	39	94.8 (67.4, 129.6)	377	916.3 (826.5, 1013.2)
Age, years
< 25	150,747	124	82.3 (68.4, 98.1)	1,247	827.2 (782.1, 874.2)
25–34	460,957	333	72.2 (64.7, 80.4)	3,777	819.4 (793.6, 845.8)
≥ 35	92,505	82	88.6 (70.5, 110.0)	919	993.5 (930.5, 1059.5)
Parity
0	391,891	295	75.3 (66.9, 84.4)	3,364	858.4 (829.8, 887.8)
1	224,711	168	74.8 (63.9, 87.0)	1,801	801.5 (765.0, 839.2)
≥ 2	80,343	69	85.9 (66.8, 108.7)	702	873.8 (810.6, 940.5)
Comorbidity^b
No	640,346	436	68.1 (61.8, 74.8)	4,840	755.8 (734.8, 777.4)
Yes	63,863	103	161.3 (131.7, 195.6)	1,103	1727.1 (1627.5, 1831.2)
Multiple birth
No	685,147	509	74.3 (68.0, 81.0)	5,430	792.5 (771.7, 813.8)
Yes	19,062	30	157.4 (106.2, 224.6)	513	2691.2 (2466.1, 2930.9)
Socioeconomic deprivation^c
No	525,114	396	75.4 (68.2, 83.2)	4,328	824.2 (799.9, 849.0)
Yes	139,588	115	82.4 (68.0, 98.9)	1,320	945.6 (895.5, 997.8)
Period
1988–1995	244,545	146	59.7 (50.4, 70.2)	1,590	650.2 (618.7, 682.8)
1996–2003	213,761	159	74.4 (63.3, 86.9)	2,164	1012.3 (970.3, 1055.7)
2004–2012	245,903	234	95.2 (83.4, 108.2)	2,189	890.2 (853.4, 928.1)
Total	704,209	539	76.5 (70.2, 83.3)	5,943	843.9 (822.7, 865.6)
^aNumber of days with maximum daily temperature ≥ 30°C during weeks 2–8 postconception. ^bPreexisting diabetes, hypertension, or heart disease; obesity; blood, thyroid, epilepsy or mood disorders; connective tissue diseases; tobacco or substance abuse. ^cPoorest fifth of the population for socioeconomic area data on median personal income, proportion of the population with no high school diploma, and unemployment rate.