Fig 5. NK cells from immunologic non-responders mediate CD4+ T cell death in vitro.

NK cells were isolated from 5 healthy controls and 5 ART-treated viral-suppressed immunologic non-responders. CD4+ T cells were isolated from the same healthy donor. CD4+ T cells were cultured with isolated NK cells at a ratio of 1:3. The percentage of CD4+ T cell cytolysis was analyzed. (A) Dot plots were shown from a representative healthy control donor and a representative HIV+ donor. (B) The median percentages of CD4+ T cell cytolysis were shown with co-cultured NK cells from healthy controls and immunologic non-responders.