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. 2017 Jan 11;12(1):e0169922. doi: 10.1371/journal.pone.0169922

Fig 3. IL-37 suppresses inflammatory responses in mycobacterial-infected macrophages and mice.

Fig 3

(A- B) ELISA detection of IL-6 (A) and TNF-α (B) in WT and IL-37-Tg macrophages infected with H37Rv at MOI = 5 for indicated times. Results are the mean±SEM and representative of 3 independent experiments with triplicates each. (C-D) Kinetics of IL-6 (C) and TNF-α (D) production detected by ELISA in the lung of WT and IL-37-Tg mice infected with BCG. Results are the mean±SEM and are pooled from two independent experiments. n = 7 or 8 for each time point; two way ANOVA with Bonferroni’s post test. *, p<0.05; **, p<0.01.