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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Breast Cancer Res Treat. 2016 Nov 19;161(2):363–373. doi: 10.1007/s10549-016-4051-1

Table 5.

Time from study registration to report of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) by chemotherapy regimen received

Chemotherapy regimen n Median (mean)
Years to AMLa
Min Max Standard deviation
AML events (n = 30)
 AC 16 1.65 (2.67) 0.79 12.52 0.74
 ACTb 13 2.48 (2.78) 0.88 6.98 0.44
 CMF 1 7.26 (7.26) 7.26 7.26
MDS events (n = 17)
 AC 7 2.74 (3.95) 2.03 7.84 0.83
 ACTb 8 3.23 (3.47) 0.29 7.16 0.82
 Capecitabine 1 2.22 (2.22) 2.22 2.22
 CMF 1 5.87 (5.87) 5.87 5.87

AC doxorubicin and cyclophosphamide, ACT AC-paclitaxel, CMF cyclophosphamide, methotrexate, 5-fluorouracil

a

From study registration

b

Including all schedules of administration