Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Strategies for siRNA delivery from hydrogels include encapsulation within a nanoparticle or as an siRNA conjugate to permit cell transfection. Towards hydrogel design, polymer charges are varied and degradable sequences and crosslinking mechanisms control the rate at which siRNA is released. Upon release, nanoparticles or free siRNA are able to interact with cell membranes and enter the cell, leading to gene silencing.
