Table 1.
Baseline characteristics of the cohort as stratified by age
| Variable | Age < 90 (n=175) | Age > 90 (n= 18) | p=value |
|---|---|---|---|
| Age, y, mean (SD) | 68.4 (±13.7) | 91.9 (±2.3) | |
| Female | 75 (43%) | 11(61%) | 0.212 |
| Hypertension | 139 (79.4%) | 15 (83.3%) | 0.999 |
| Hyperlipidemia | 101 (57.7%) | 10 (55.5%) | 0.999 |
| Atrial Fibrillation | 63 (36%) | 13 (72.2%) | 0.004 |
| IV tPA | 84 (48%) | 12 (66.6%) | 0.146 |
| NIHSS, mean (SD) | 16.92(6.27) | 18.28 (5.44) | 0.379 |
| Pre stroke mRS (CI) | 0.24 (0.17–0.35) | 0.77 (0.44–1.28) | 0.005 |
| mRS 0 | 130 | 5 | |
| mRS 1 | 24 | 8 | |
| mRS 2 | 9 | 4 | |
| mRS 3 | 12 | 1 | |
| Location of arterial occlusion | |||
| Internal carotid artery | 51 (29.1%) | 6 (33.3%) | 0.920 |
| Middle cerebral artery | 109 (62.3%) | 12 (66.7%) | 0.910 |
| Basilar artery | 8 (4.6%) | 0 (0.0%) | 0.999 |
| Others | 7 (1.7%) | 0 (0.0%) | 0.999 |
| Complete recanalizationa | 109 (62.3%) | 12 (66.6%) | 0.999 |
| Infarct Volume, mL (CI) | 84 [68–104] | 130 [83–203] | 0.0832 |
| Parenchymal Hemorrhage | 46 (26.3%) | 6 (33.3%) | 0.579 |
| mRS 3–6 at 90 days | 91 (52%) | 16 (88.9%) | 0.0027 |
| mRS 4–6 at 90 days | 73 (41%) | 14 (77%) | 0.006 |
Data are n (%) or mean (± standard deviation SD). CI=95% confidence interval; IV=intravenous; mRS=modified Rankin Scale; NIHSS=National Institutes of Health Stroke Scale; PH=Parenchymal Hemorrhage Type 1 (PH1) and 2 (PH2); tPA=recombinant tissue plasminogen activator
a
Defined as Thrombolysis In Cerebral Infarction (TICI) 2b and 3
b
Defined as PH1 and PH2