Table 3.
Prevalence of amino acids at positions 37, 41, and 55 in peripheral blood Vpr sequences collected using deep sequencing. Samples from seven HIV-1-infected patients were sequenced using NGS focused on the vpr open reading frame in genomic DNA. The prevalence of each amino acid at a site is shown as a fraction of the total. Bold text highlights the niVpr variants identified in Figure 2.
| Patient | E37 | G37 | I37 | M37 | P37 | V37 | G41 | N41 | S41 | A55 | E55 | T55 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A0103 | 0.25 | 0.75 | 1.00 | 1.00 | ||||||||
| A0432 | 1.00 | 1.00 | 1.00 | |||||||||
| A0438 | 0.07 | 0.51 | 0.41 | 0.88 | 0.12 | 0.71 | 0.29 | |||||
| A0451 | 1.00 | 1.00 | 1.00 | |||||||||
| A0457 | 1.00 | 1.00 | 1.00 | |||||||||
| A0460 | 1.00 | 1.00 | 1.00 | |||||||||
| A0461 | 1.00 | 1.00 | 1.00 | |||||||||
| A0467 | 1.00 | 1.00 | 1.00 | |||||||||
| A0469 | 1.00 | 1.00 | 1.00 |