Table 3.

Examples of coded reasons with matching and non-matching actions

Slow Accrual Reason	Proposed Action	Action Matches Reason?
Strict eligibility criteria	Broaden eligibility criteria	Well matched
Extended delays for IRB/site activation	Activation/IRB approval at planned participating site	Well matched
High rate of screen failures	Promotion of trial – internal	Potential to influence
Longer than expected pre-specified halt/change to enrollment due to interim analyses, stopping rules, data review by DMC	Add new institutions	Does not match
Longer than expected pre-specified halt/change to enrollment due to interim analyses, stopping rules, data review by DMC	No action provided	Does not match