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. 2016 Nov 20;73(2):197–203. doi: 10.1007/s00228-016-2163-5

Table 2.

Cumulative doses self-reported by the 93 patients in the previous 3 months and hair concentrations for the 23 drugs

Self-reported drug (n) Cumulative doses (mean ± SD, mg) Hair concentrations (mean ± SD, pg/mg) r P value
Alprazolam (7) 41.82 ± 44.09 66.95 ± 65.70 0.5339 0.431
Amitriptyline (24) 1877.50 ± 2218.01 2798.10 ± 3391.70 0.7485 0.015*
Citalopram (16) 1760.63 ± 868.18 2563.88 ± 1906.90 1.6653 <0.001**
Clomipramine (3) 6956.70 ± 11,513.30 3730.00 ± 3516.37
Clonazepam (1) 90.00 90.00
Delorazepam (22) 235.86 ± 395.16 150.26 ± 330.10 0.2563 <0.000**
Diazepam (3) 110.00 ± 43.59 1033.33 ± 1280.80
Duloxetine (16) 4224.40 ± 1608.80 8520.75 ± 7627.80 1.2657 <0.001**
Fluoxetine (4) 2700.00 ± 1800 20,578.25 ± 22,440.20
Flurazepam (1) 1350 359.00
Levomepromazine (1) 2250.00 1037.00
Levosulpiride (4) 2163.00 ± 3101.09 254.75 ± 217.40
Lorazepam (7) 241.07 ± 298.13 263.71 ± 299.30 0.9995 <0.001**
Lormetazepam (1) 180.00 1207.00
Mirtazapine (2) 2700.00 ± 1909.19 586.50 ± 227.90
Paroxetine (4) 1350.00 ± 492.95 804.83 ± 709.90
Quetiapine (2) 506.30 ± 79.50 470.40 ± 508.00
Sertraline (4) 5812.50 ± 3986.30 24,600.25 ± 28,087.20
Topiramate (12) 4774.17 ± 5343.41 2414.17 ± 2028.90 0.2210 0.217
Trazodone (1) 900.00 6379.00
Triazolam (1) 22.50 16.00
Venlafaxine (6) 6750.00 ± 6161.88 1864.14 ± 2174.90 0.3054 0.012*
Zolpidem (2) 2475.00 ± 2863.78 1718.00 ± 1750.80

Linear regression analysis for drugs taken by at least five patients

r slope value

*P < 0.05

**P < 0.01