Table 1.
Serial TREC and KREC levels in PID patients with abnormal screening test results
| TREC copies/3.2 mm blood spot | KREC copies/3.2 mm blood spot | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | Sex | Gestational age (weeks) | Diagnosis | Result 1 | Result 2 | Result 3 | Result 4 | Result 1 | Result 2 | Result 3 | Result 4 |
| 1 | Male | 34 | Artemis deficiency | Day 2 0 |
Day 8 0 |
Day 14 0 |
Day 24 0 |
Day 2 0 |
Day 8 0 |
Day 14 0 |
Day 24 0 |
| 2 | Male | 39 | Ataxia-telangiectasia | Day 2 5 |
Day 25 5 |
Day 43 3 |
Day 51 3 |
Day 2 7 |
Day 25 10 |
Day 43 21 |
Day 51 19 |
| 3 | Male | 36 | Unknown genetic defecta | Day 2 7 |
Day 27 4 |
Day 34 5 |
Day 94 1 |
Day 2 205 |
Day 27 732 |
Day 34 504 |
Day 94 250 |
aT cell lymphopenia and hypogammaglobulinemia. At follow-up at 15 months of age, the child’s hypogammaglobulinemia had resolved but a persistent idiopathic CD3+ T cell lymphopenia (absolute CD3+ count = 0.9 × 109/L) was evident