Table 1.
Baseline characteristics of elderly patients (age ≥70 years) with and without vascular disease
| With vascular disease | Without vascular disease | |||
|---|---|---|---|---|
| PROSPER (n = 2550) | SMART (n = 1442) | PROSPER (n = 3253) | ASCOT-LLA (n = 1893) | |
| Demographics | ||||
| Male gender (n, %) | 1453 (57.0) | 1062 (73.7) | 1350 (41.5) | 1525 (80.6) |
| Age (years) | 75.7 (3.4) | 73.6 (2.7) | 75.1 (3.3) | 74.1 (2.7) |
| Country of residence (n, %) | ||||
| Scotland/UKa | 1232 (48.3) | 1288 (39.6) | 990 (52.3) | |
| Ireland | 845 (33.1) | 1338 (41.1) | 19 (1.0) | |
| The Netherlands | 473 (18.5) | 1442 (100) | 627 (19.3) | |
| Denmark | 133 (7.0) | |||
| Finland | 126 (6.7) | |||
| Iceland | 11 (0.6) | |||
| Norway | 205 (10.8) | |||
| Sweden | 409 (21.6) | |||
| Current smoker (n, %) | 474 (18.6) | 238 (16.5) | 1084 (33.3) | 402 (21.2) |
| N medications (median, IQR) | 4 (3–6) | 5 (4–7) | 3 (2–4) | 2 (1–3) |
| Statin treatment (n, %) | 1299 (50.9) | 885 (61.4) | 1591 (48.9) | 939 (49.6) |
| Medical history | ||||
| Diabetes (n, %) | 224 (8.7) | 293 (20.3) | 399 (12.3) | 514 (27.2) |
| Cardiovascular disease (n, %) | ||||
| Coronary artery disease | 1524 (59.8) | 610 (42.3) | 0 (0) | 0 (0) |
| Cerebrovascular disease | 425 (16.7) | 276 (19.1) | 0 (0) | 0 (0) |
| Peripheral artery disease | 206 (8.1) | 238 (16.5) | 0 (0) | 0 (0) |
| Polyvascular disease | 395 (15.5) | 318 (22.1) | 0 (0) | 0 (0) |
| Physical examination | ||||
| Heart rate (beats/min) | 65.2 (11.6) | 66.0 (14.1) | 67.2 (11.6) | 69.6 (12.3) |
| Systolic blood pressure (mmHg) | 152 (22) | 148 (22) | 157 (22) | 170 (19) |
| Laboratory measurements | ||||
| LDL cholesterol (mmol/l) | 3.8 (0.8) | 3.8 (1.2) | 3.8 (0.8) | 3.5 (0.7) |
| HDL cholesterol (mmol/l) | 1.2 (0.3) | 1.3 (0.4) | 1.3 (0.4) | 1.3 (0.4) |
| eGFR (ml/min/1.73 m2) | 58.8 (14.3) | 66.8 (16.7) | 61.0 (14.7) | 63.6 (11.8) |
Data are displayed as mean (SD) unless indicated otherwise
a UK United Kingdom