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. 2016 Nov 21;28(2):376–383. doi: 10.1007/s13361-016-1544-4

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Kaplan-Meier survival plots of prognostic biomarkers discovered from MALDI-TOF MSI datasets. Prognostic metabolite ions were found from a sub-dataset of myxofibrosarcomas and from a dataset consisting of all soft tissue sarcomas (non-OS subset). (a) Shows a metabolite ion (m/z 240.88) that was found when the analysis was limited to undifferentiated areas, and was indicative for poor survival of soft tissue sarcoma patients; (b) and (c) show two metabolite ions (m/z 180.90 and m/z 160.84) indicating poor survival in soft tissue sarcoma patients and myxofibrosarcoma patients, respectively. P-values listed are calculated using a log-rank test in Kaplan-Meier analysis