| Sites |
Evidence of 17β-estradiol synthesis |
References |
|
| Cyp19 mRNA |
Cyp19 protein |
17β-estradiol |
|
| Brain |
Astrocyte (rat, mouse, human), Hippocampus and hypothalamus (rat, mouse, monkey, human) |
Astrocyte (mouse), GnRH (rat), Dentate gyrus/ pyramidal cell (rat, mouse, human, monkey), Interneurons (human), Granular cell (human, monkey), Purkinje cell (human, mouse), Ependymal andsubependymal cell (human). |
Astrocyte (rat, monkey). |
(7-16)
|
| Fat |
Stromal cell (human), Adipocyte (human) |
Stromal cell (human), Adipocyte, mesenchymal cell (human) |
|
(13-16)
|
| Bone |
Osteoblast (human) |
Osteoblast (human) |
Osteoblast (human) |
(17-19)
|
| Liver |
HepG2 hepatoma andhepatocellular carcinoma (human), Hepatocyte (porcine). |
HepG2 hepatoma and hepatocellular carcinoma (human) |
HepG2 hepatoma and hepatocellular carcinoma (human) |
(20-22)
|
| Adrenal gland |
Adrenocortical cell (human, porcine, rat) |
Adrenocortical cell (human) |
Adrenocortical cell (rat) |
(22-24)
|
| Intestine |
Parietal cell (rat) |
Parietal cell (rat) |
Parietal cell (rat) |
(25) |
| Skin |
Fibroblast (human). Keratinocyte (human). |
Fibroblast (chicken, human), Keratinocyte (human) |
Fibroblast (chicken) |
(26-28)
|
| Blood vessel |
Smooth muscle cell (human, rat, bovine) |
Smooth muscle cell (human, rat, bovine) |
|
(29-31)
|
| Spleen |
T cell (mouse) |
T cell (mouse) |
|
(32) |
