Table 4. Pathological factors and association with anastomotic leakage.
| Characteristic | No leak (n=587), n (%) | Leak (n=122), n (%) | Total (n=709), n (%) | P value |
|---|---|---|---|---|
| TNM staging | 0.2208 | |||
| I | 139 (23.68) | 22 (18.03) | 161 (22.71) | |
| II | 173 (29.47) | 36 (29.51) | 209 (29.48) | |
| III | 193 (32.88) | 46 (37.70) | 239 (33.71) | |
| Uncertain | 82 (13.97) | 18 (14.75) | 100 (14.10) | |
| Pathologic subtype | 0.6610 | |||
| Squamous cell carcinoma | 572 (97.44) | 118 (96.72) | 690 (97.32) | |
| Adenocarcinoma | 15 (2.56) | 4 (3.28) | 19 (2.68) | |
| Tumor location | 0.7562 | |||
| Upper | 175 (29.81) | 31 (25.41) | 206 (29.06) | |
| Middle | 246 (41.91) | 60 (49.18) | 306 (43.16) | |
| Lower | 138 (23.51) | 25 (20.49) | 163 (22.99) | |
| Multiple | 28 (4.77) | 6 (4.92) | 34 (4.79) | |
| Tumor length (cm) | 0.301 | |||
| <3 | 128 (21.81) | 19 (15.57) | 147 (20.73) | |
| ≥3 and <5 | 248 (42.25) | 55 (45.08) | 303 (42.74) | |
| ≥5 | 211 (35.95) | 48 (39.34) | 259 (36.53) | |
| Neoadjuvant therapy response | n=68 | n=12 | n=80 | 0.0931 |
| Mild | 23 (33.82) | 1 (8.33) | 24 (30.00) | |
| Moderate | 19 (27.94) | 4 (33.33) | 23 (28.75) | |
| Severe | 26 (38.24) | 7 (58.33) | 33 (41.25) |