Fig. 3. Cordycepin promoteschondrogenesis through BMP pathway but inhibits chondrocyte hypertrophy through Notch pathway. (A) Relative mRNA expression levels of Hey1, Nrf2, Id2, and PI3K from MSCs induced by chondrogenic medium (day 3, 7, and 14). (B) Relative mRNA expression levels of Bapx1, PI3K, β-catenin, and Hey1 from MSCs in different groups (day 17, 21, and 28). (C) Relative mRNA expression levels of Fak, PI3K, β-catenin, and Hey1 from ATDC5 cells induced by hypertrophic medium in different groups (day 3, 7, and 14).
