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. Author manuscript; available in PMC: 2017 Jan 12.
Published in final edited form as: Small. 2015 Jan 7;11(15):1801–1810. doi: 10.1002/smll.201403248

Figure 3.

Figure 3

A) Optical microscopy images of HeLa cells after incubation with 80 × 10−12 m GNS-N/C 3–5 for 4 h. Scale bar: 100 μm. The clean background circled in dashed lines indicates the excellent biostability of PEGylated mixed-charge GNSs. B) Cellular uptake of PEGylated GNSs determined by ICP after incubation with 80 × 10−12 m GNS-NH2, GNS-COOH, and GNS-N/C 3–7 for 4 h. Statistical difference has been indicated by asterisks. C) Plot of ICP data quantifying the degree of cellular uptake as a function of the zeta potential of PEGylated mixed-charge GNSs.