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. 2017 Jan 9;8:13994. doi: 10.1038/ncomms13994

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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PCA score plots for (a) all populations (both Pco₂) (Vigo-red, Île de Ré-orange, Roscoff-yellow, Millport-green, Trondheim-blue, Tromsø-purple). (b) Control Pco₂. (c) Elevated Pco₂. (d) Vigo, (e) Île de Ré, (f) Roscoff, (g) Millport, (h)Trondheim, (i)Tromsø PLS-DA score plots for forward selected metabolomic profiles for each population (individual data, n=30). Open circles indicate current Pco₂ and filled circles indicate elevated Pco₂.