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. 2017 Jan 12;7:38600. doi: 10.1038/srep38600

Table 2. Identified QTSs for cholesterol using full model approach.

Chr_SNP_Alleles Gene Effect Estimate SE −log10PEW h2 (%)
1_rs629301_T/G CELSR2 a 4.94 0.40 34.47 1.46
2_rs478442_A/C 132 kb 5′ of APOB a 5.73 0.39 47.61 1.97
de1 −3.85 0.85 5.23 1.32
de4 5.40 1.26 4.75
4_rs7694118_C/T 1.8 kb 5′ of PCDH10 d 3.11 0.64 6.01 0.58
de1 8.31 2.12 5.04 3.18
de3 −6.08 0.96 9.60  
5_rs17409624_G/A DROSHA a 2.14 0.45 5.70 0.27
7_rs6465748_G/A 9.6 kb 5′ of MYH16 a −3.11 0.35 18.43 0.58
ae3 −4.67 0.68 11.12 1.22
ae4 4.33 0.71 9.04
8_rs10503377_C/T 139 kb 5′ of SGK223 a 3.16 0.42 13.50 0.60
11_rs10768634_T/C OR52A1 d −3.45 0.64 7.19 0.71
11_rs7124873_G/A 10 kb 3′ of MMP13 a 2.57 0.44 8.13 0.40
14_rs10483461_C/T 117 kb 3′ of BRMS1L a 2.35 0.34 11.05 0.33
ae3 4.02 0.69 8.17 0.97
15_rs12595211_G/A ETFA a −2.52 0.42 8.51 0.38
16_rs1532625_G/A CETP a −2.85 0.43 10.46 0.49
17_rs2649485_C/T 3.3 kb 5′ of CCDC144B a −2.58 0.45 8.12 0.40
19_rs1654452_C/T RDH13 a −2.02 0.43 5.64 0.25
2_rs478442_A/C  ×  132 kb 5′ of APOB  ×  aa 2.38 0.46 6.77 0.34
4_rs7694118_C/T 1.8 kb 5′ of PCDH10 da 3.59 0.67 7.09 0.77
7_rs2264802_C/A  ×  SKAP2 × UFM1 aa −4.71 0.44 26.41 1.33
13_rs9548318_G/A ad −6.14 0.86 12.16 2.26
10_rs12246594_A/T  ×  SORCS1 × ETFA aa 7.46 0.44 13.34 3.34
15_rs12595211_G/A

Chr_SNP_Alleles: chromosome_SNP_major/minor alleles; Gene: the near or holder genes corresponding to QTSs; Effect: genetic effects of QTSs, a = additive effect, d = dominance effect, aa = additive-additive epistasis effect, ad = additive-dominance epistasis effect, da = dominance-additive epistasis effect, ae3 = A-A specific additive effect, ae4 = H-A specific additive effect, de1 = E-A specific dominance effect, de3 = A-A specific dominance effect, de4 = H-A specific dominance effect; Estimate: the estimated genetic effects; −log10PEW: minus log10 (experimental-wise P-value); h2 (%) refers heritability in percentage.