Table 3. Monte-Carlo simulation study of full model approach.
Chr_SNP_Alleles | Effect | Parameter | Estimate | SE | Power (%) |
---|---|---|---|---|---|
1_rs629301_T/G | a | 4.94 | 5.80 | 0.80 | 100 |
ae4 | 1.75 | 1.90 | 0.29 | 15 | |
1_rs2499595_G/A | a | 1.86 | 1.96 | 0.52 | 44 |
ae1 | 1.36 | 1.90 | 0.38 | 23 | |
ae2 | −3.73 | −3.20 | 0.57 | 37 | |
ae4 | 1.94 | 2.43 | 0.51 | 20 | |
2_rs478442_A/C | a | 5.73 | 5.19 | 0.53 | 81 |
ae1 | −2.37 | −0.46 | 2.93 | 7 | |
de1 | −3.85 | 0.58 | 3.82 | 14 | |
de3 | −2.91 | −3.83 | 2.04 | 42 | |
de4 | 5.40 | 3.84 | 1.88 | 27 | |
3_rs7624679_C/T | a | 1.47 | 2.31 | 0.40 | 9 |
de4 | −1.81 | −3.54 | 1.97 | 2 | |
4_rs7694118_C/T | d | 3.11 | 2.56 | 1.38 | 50 |
de1 | 8.31 | 6.38 | 1.61 | 51 | |
de3 | −6.08 | −3.81 | 1.94 | 51 | |
5_rs17409624_G/A | a | 2.14 | 2.31 | 0.47 | 78 |
ae3 | 3.14 | 2.99 | 0.85 | 71 | |
ae4 | −3.00 | −2.95 | 0.73 | 69 | |
7_rs6465748_G/A | a | −3.11 | −2.85 | 2.15 | 37 |
d | 2.14 | 4.41 | 1.58 | 29 | |
ae1 | 1.55 | 1.26 | 1.72 | 20 | |
ae3 | −4.67 | −5.92 | 2.43 | 35 | |
ae4 | 4.33 | 4.51 | 1.75 | 34 | |
8_rs10503377_C/T | a | 3.16 | 3.16 | 0.75 | 73 |
ae1 | −2.12 | −2.29 | 0.68 | 61 | |
ae2 | 4.74 | 4.41 | 1.32 | 69 | |
ae4 | −2.30 | −2.59 | 0.57 | 44 | |
11_rs10768634_T/C | a | −1.15 | 0.72 | 1.05 | 21 |
d | −3.45 | −3.93 | 0.82 | 55 | |
11_rs7124873_G/A | a | 2.57 | 2.97 | 0.42 | 76 |
14_rs10483461_C/T | a | 2.35 | 2.86 | 2.03 | 67 |
d | −2.73 | −4.50 | 1.68 | 60 | |
ae3 | 4.02 | 2.96 | 1.08 | 23 | |
ae4 | −1.47 | −2.23 | 1.28 | 16 | |
15_rs12595211_G/A | a | −2.52 | −2.98 | 0.58 | 51 |
de4 | 1.94 | 2.45 | 0.63 | 15 | |
16_rs1532625_G/A | a | −2.85 | −3.19 | 0.65 | 79 |
16_rs4888652_T/C | a | 1.91 | 2.43 | 0.46 | 46 |
17_rs2649485_C/T | a | −2.58 | −2.84 | 0.39 | 64 |
18_rs9946067_T/C | a | −2.23 | −1.63 | 0.46 | 36 |
d | 2.89 | 2.70 | 0.77 | 39 | |
19_rs1654452_C/T | a | −2.02 | −2.29 | 0.53 | 70 |
d | 1.62 | 2.00 | 0.64 | 64 | |
2_rs478442_A/C × | aa | 2.38 | 2.83 | 0.69 | 12 |
4_rs7694118_C/T | ad | −2.60 | −4.14 | 1.69 | 10 |
da | 3.59 | −4.14 | 1.69 | 11 | |
16_rs4888652_T/C × | da | 2.64 | −0.58 | 1.74 | 10 |
18_rs9946067_T/C | dd | −1.95 | −3.52 | 0.95 | 8 |
7_rs2264802_C/A × | aa | −4.71 | −4.21 | 0.85 | 10 |
13_rs9548318_G/A | ad | −6.14 | −6.45 | 0.75 | 8 |
10_rs12246594_A/T× | aa | 7.46 | 6.86 | 1.08 | 12 |
15_rs12595211_G/A |
Results of Monte-Carlo simulations under scenario-I. Chr_SNP_Alleles: chromosome_QTS_major/minor alleles; Effect: mode of gene action; Parameter: true genetic effect; Estimate: average estimated effect of genetic parameters; Power (%): power of detecting effects in percentage.