Table 3. Age and sex adjusted associations of established risk factors, hs-CRP, and physical indicators with cardiovascular and all-cause mortality.

	Cardiovascular mortality				All-cause mortality
Variables	Hazard ratio	95% CI	C-statistics	P-value	Hazard ratio	95% CI	C-statistics	P-value
Basic model
Systolic blood pressure per SD change	1.8	1.2–2.7	0.77	<0.001	1.2	0.9–1.5	0.74	0.210
Antihypertensive treatment	1.4	0.6–3.6	0.73	0.459	1.1	0.6–1.9	0.74	0.777
Total cholesterol per SD change	0.9	0.6–1.4	0.74	0.601	1.0	0.8–1.3	0.74	0.909
HDL-cholesterol per SD change	0.7	0.4–1.3	0.73	0.286	0.8	0.5–1.0	0.73	0.007
Lipid-lowering treatment	2.3	0.6–8.3	0.73	0.202	1.9	0.8–4.3	0.74	0.136
Diabetes	2.0	0.7–5.7	0.74	0.195	1.9	1.0–3.6	0.74	0.038
Smoking	0.9	0.3–2.9	0.73	0.856	0.8	0.4–1.6	0.74	0.533
Body mass index per SD change	1.1	0.7–1.8	0.74	0.597	1.1	0.8–1.4	0.74	0.568
Predictive parameter
Framingham risk score per SD change	2.4	1.3–4.5	0.78	0.006	1.3	0.9–1.9	0.74	0.157
High-sensitivity CRP per SD change	1.6	1.2–2.2	0.77	0.004	1.6	1.3–1.9	0.77	<0.001
Dominant handgrip strength per SD change	0.5	0.3–0.9	0.77	0.012	0.4	0.3–0.5	0.78	<0.001
Relative handgrip strength per SD change	0.5	0.3–0.8	0.79	0.010	0.4	0.3–0.6	0.79	<0.001
Walking speed per SD change	0.7	0.4–1.1	0.74	0.132	0.8	0.6–1.0	0.74	<0.083
Peak flow rate per SD change	0.5	0.2–0.9	0.78	0.016	0.5	0.4–0.7	0.76	<0.001

CI, confidence interval; HDL, high-density lipoprotein; CRP, C-reactive protein.