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. 2017 Jan 12;7:40281. doi: 10.1038/srep40281

Figure 4. Sphingolipid depletion leads to cell wall defect.

Figure 4

Wild-type strains of S. cerevisiae (BY4741, BY4743, FY4) and C. albicans (SC5314) were tested for their sensitivity to CFW alone or in the presence of myriocin or myriocin and phytosphingosine (PHS). The sublethal concentration of myriocin sensitised the cells to CFW, which is rescued by supplementation with PHS.