Table I.
Demographic and clinicopathological characteristics of 35 GCTB denosumab-treated patients included in the present study.
| Parameter | Value |
|---|---|
| Gender, n (%) | |
| Female | 21 (60) |
| Male | 14 (40) |
| Median age, years (range) | 32 (19–74) |
| GCTB disease type, n (%) | |
| Unresectable primary tumor | 9 (26) |
| Resectable high-risk primary tumor | 26 (74) |
| Prior GCTB therapies, n (%) | |
| Biopsy only | 24 (68) |
| RT | 4 (11) |
| Subtotal resection | 3 (9) |
| Radical resection | 3 (9) |
| Surgery + adjuvant RT | 1 (3) |
| Tumor localization, n (%) | |
| Lower limb | 17 (49) |
| Tibia | 10 (29) |
| Femur | 6 (17) |
| Fibula | 1 (3) |
| Upper limb | 11 (31) |
| Humerus | 4 (11) |
| Radius | 5 (14) |
| Ulna | 1 (3) |
| Metacarpal bone | 1 (3) |
| Axial | 7 (20) |
| Sacrum | 5 (14) |
| Ilium | 1 (3) |
| Ischium | 1 (3) |
GCTB, giant cell tumor of bone; RT, radiotherapy.