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. 2016 Oct 21;12(6):4896–4904. doi: 10.3892/ol.2016.5304

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Copyright: © Takata et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Expression of PDIA3 in HCC tissue. (A) The representative histology of HCC with trabecular growth pattern and non-HCC tissue. Hematoxylin & eosin staining (magnification, ×40). (B) Intense expression of PDIA3 was observed in the HCC tissue compared with the non-HCC tissue (magnification, ×40). (C) Healthy hepatocytes exhibited only weak PDIA3 staining (magnification, ×400). (D) Clear cytoplasmic staining occurred in HCC cells (magnification, ×400). Representative immunostaining of HCC tissue with (E) high expression and (F) low expression of PDIA3 (magnification, ×400). PDIA3, protein disulfide-isomerase A3; HCC, hepatocellular carcinoma.