. 2016 Oct 21;12(6):4949–4956. doi: 10.3892/ol.2016.5303

Table I.

Infinium HumanMethylation450 Beadchip assay data for HPV positive vs. HPV negative HNSCC samples for 11 genes.

Gene name	Chromosome	HPV status	Mean β	SD	Ratio of HPV positive vs. HPV negative	P-value	Methylation
C14orf162/CCDC177	14	Positive	0.161	0.041	0.579	0.019^a	Hypo
		Negative	0.278	0.034
CDH8	4	Positive	0.479	0.062	1.640	0.004^a	Hyper
		Negative	0.292	0.055
CRMP1	4	Positive	0.208	0.058	1.155	0.749	Hyper
		Negative	0.180	0.058
ELMO1	7	Positive	0.578	0.067	1.234	0.026^a	Hyper
		Negative	0.468	0.033
HTR1E	6	Positive	0.433	0.062	1.357	0.027^a	Hyper
		Negative	0.319	0.060
MEI1	22	Positive	0.318	0.072	0.849	0.008^a	Hypo
		Negative	0.531	0.087
MSX2	5	Positive	0.394	0.081	2.213	0.009^a	Hyper
		Negative	0.178	0.065
PCDH10	4	Positive	0.333	0.103	1.524	0.166	Hyper
		Negative	0.220	0.023
PCDHB11	5	Positive	0.548	0.074	1.302	0.042^a	Hyper
		Negative	0.421	0.076
PITX2	4	Positive	0.416	0.112	1.386	0.138	Hyper
		Negative	0.300	0.088
SYN2	3	Positive	0.399	0.115	1.013	0.781	Hyper
		Negative	0.394	0.104

P<0.05, indicates a statistically significant difference. Cohort of 8 samples (4 HPV+HNSCC, 4 HPV-HNSCC). HNSCC, head and neck squamous cell carcinoma; HPV, human papilloma virus; chrom, chromosome; SD, standard deviation; meth, methylation status; hypo, hypomethylated; hyper, hypermethylated; C14orf162/CCDC177; chromosome 14 open reading frame 162/coiled-coil domain containing 177; CDH8, cadherin 8; CRMP1, collapsin response mediator protein 1; ELMO1, engulfment and cell motility 1; HTR1E, 5-hydroxytryptamine receptor 1E; MEI1, meiotic double-stranded break formation protein 1; MSX2, msh homeobox 2; PCDH10, protocadherin 10; PCDHB11, protocadherin β-11; PITX2, paired like homeodomain 2; SYN2, synapsin II.