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. 2016 Oct 14;12(6):3583–3588. doi: 10.3892/etm.2016.3807

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Copyright: © Dong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Changes in MWT and TWL in incision pain rats were recorded after intrathecal delivery of the 5-HT_2AR agonist, TCB-2, and the 5-HT_2AR antagonist, ketanserin, at baseline and 1–7 days after. (A) MWT increased in the incision+TCB-2 group, while it decreased in the incision+ketanserin group after 1 day (*P<0.05, **P<0.01), compared with the incision+DMSO group. (B) Changes in TWL were detected in incision pain rats after intrathecal delivery of the 5-HT_2AR agonist, TCB-2, and the 5-HT_2AR antagonist, ketanserin (*P<0.05), compared with the incision+DMSO group. MWT, mechanical withdrawal threshold; TWL, thermal withdrawal latency; 5-HT_2AR, 5-hydroxytryptamine 2A receptor; DMSO, dimethyl sulfoxide.