Figure 5.

ROR2 overexpression suppresses canonical Wnt signaling. Western blotting was performed to examine the protein expression levels of (A) β-catenin in the nucleus and (B) c-Myc in AGS cells transfected with the pcDNA3.1-ROR2 plasmid. GAPDH was used as an internal reference. AGS cells transfected with the blank vector and non-transfected AGS cells were used as controls. **P<0.01, vs. AGS. ROR2, receptor tyrosine kinase-like orphan receptor 2; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.