Effect of forbesione administration on the general parameters and histopathological assessment of inflammation in a hamster model. Effects of oral forbesione administration on (A) body weight, (B) food intake and (C) water intake. Compared with the control group, body weight, food intake and water intake were significantly increased in the forbesione-treated group. Values are presented as the mean ± standard deviation. *P<0.05, **P<0.01, ***P<0.001. Representative hematoxylin and eosin staining of the (D) liver, (E) kidney and (F) stomach (forestomach and glandular stomach) of hamsters following forbesione administration for 4 weeks. Forb, forbesione; DMSO, dimethyl sulfoxide.