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. 2016 Oct 18;12(6):4685–4698. doi: 10.3892/ol.2016.5284

Table V.

Histopathological features of liver tissues and grading criteria level in each experimental group.

Experimental groups

Histopathology Score Control, n=6 n (%) Forbesione 50 mg/kg, n=6 n (%)
Periportal inflammationa 0 5 (83.3) 5 (83.3)
1 1 (16.7) 1 (16.7)
2 0 (0.0) 0 (0.0)
3 0 (0.0) 0 (0.0)
4 0 (0.0) 0 (0.0)
Focal inflammationb 0 5 (83.3) 6 (100.0)
1 1 (16.7) 0 (0.0)
2 0 (0.0) 0 (0.0)
3 0 (0.0) 0 (0.0)
4 0 (0.0) 0 (0.0)
a

Periportal or periseptal interface hepatitis (piecemeal necrosis) score: 0, none; 1, mild (focal, few portal areas); 2, mild/moderate (focal, the majority of portal areas); 3, moderate (continuous around <50% of tracts or septa); and 4, severe (continuous around >50% of tracts or septa). P=1.00.

b

Focal inflammation score: 0, none; 1, ≤1 focus/X10 objective; 2, 2–4 foci/X10 objective; 3, 2–4 foci/X10 objective; and 4, 2–4 foci/X10. P=0.182.